Global nuclear power generation has stagnated since the early 2000s. However, most decarbonization outlooks foresee a significant increase in the role of nuclear, for base-load low-carbon electricity. At the same time, volatile fossil fuel prices and the invasion of Ukraine by Russia are driving heightened scrutiny of supply chain security. At COP28, more than 20 countries pledged to triple nuclear energy capacity by 2050. Could a regeneration of nuclear power be on the way? What role will nuclear play in a future lower-carbon energy mix? Can new emerging nuclear technologies accelerate the decarbonization of power systems?